Figured it out! I was using "WBFS Manager 3.0" to convert the ISO on one hard to a wbfs file on another hard drive. It did not work when at least one of the hard drives was connected via USB. Like I said before, the Wii would reset when I tried to run the game. The solution was to attach both sata hard drives to internal connections in the PC - then use WBFS Manager 3.0. I guess the USB interface didn't work with the WBFS Manager conversion process. Thanks for your help everyone!