Ok, exchanged my motion plus at Game Stop and just tried to play Red Steel 2. The game loads fine, but the remote is still losing sync constantly. The only other thing I can think of is that my remotes are NYKO brand. Their earlier "WAND" had problems with the Motion Plus, but when I called they said that they wouldn't work at all if the motion plus was plugged into them. Mine work until I start a game that requires the motion plus. Any ideas? Interested to see if the original poster has the NYKO remotes as well.