The iso file was simply a bad image. Replacing the file fixes the problem.
@ robbobnbill I don't think that removing adding/deleting files has anything to do with the game stop working. As long as games are added through a recommended program i.e. WBFS Manager, there should not be any problems. I myself have no problems removing adding games on my wbfs formatted HDD, since your not messing with the actual iso file, but with the HDD only.
@ Lavor glad you got it working, enjoy it!