yes like dark mod says you will semi brick your wii .....u wont be able to access the wii settings menu until a new game thats NTSC requires an update and this will fix it...if your wii is not at 3.3 you can use the following disc to unbrick your wii with no issues
[Only Registered Users Can See Links. Click Here To Register]
if you have 3.3 update we always tell our customers and offer to install the homebrew channel for free so they dont have to worry about bricking since they can always slap the disc in and unbrick