I to am having a problem with Anno. However my copies do not lock up, but rather I get a disc read error at the in game title screen. Could this be a similar problem?
I'm running NG 7 with CIOS rev14 on 4.0U.
I've tried both the NTSC and PAL versions of the game. I'm using the same discs as always, which have worked flawlessly in the past.