This guide worked well.
I am currently using USB Loader GX and running it from my 500gb Paritioned HDD I have no problems yet.
But for other people that have had issues, I'm not sure if it was writen on here yet but were the iso's brick blocked and region free'd?
There's a few guides and tools on the internet on this game so keep searching for your solution.
People just may be missing something small.
Great guide thanks for the help!