"He have also encountered the controller not being usable when using Dios Mios. This was a first party controller and he could not believe it because it used to work in the first release of DM and also DML. How did he fix it? It's funny but he loaded a retail gamecube disc, then played a few minutes. He exited and removed the retail gamecube disc and booted usb loader gx and tried the game he loaded from USB again. Controller now Works! This trick was done on 2 Wiis. He hope he don't do anything that will render the controller useless again but the question is: Why did he have to play a retail game for the controller to work in Dios Mios USB? Why does it now work thereafter? He find it very wierd. "
I personally never had any issues with GC cons.
DIOS MIOS 2.2 and new USB Loaders may have issues with old game saves and old game settings.
this is why I said this in a old post:
"go in your SD/apps folder/usbloader_gx and remove GXGameSettings.GFG"
because the old game settings could cause issues with new DIOS MIOS and new USB Loaders